National electronic Library for Medicines Medicines Management Overview March 2013 TABLET SPLITTING Annotated bibliography of publications

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A synopsis attempts to provide a general overview of the main themes which emerge. It may be concluded that the uniformity of tablet segments depends on a wide range of variables, involving the composition, manufacture and scoring of the tablet, the means used to divide it and the ability of the person carrying out the division. For drugs with a wide therapeutic range and long half-life, lack of uniformity may not be a problem, but in other cases it may become critical.

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تاریخ انتشار 2013